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Your doctor will probably let you know not to take tramadol if you are taking one or more of those medications, or have taken them within the previous 2 weeks.</p><p> Meals and Drug Administration, there's an increased danger of serotonin syndrome as a result of combining selective serotonin reuptake inhibitors (SSRIs) and selective serotonin-norepinephrine reuptake inhibitors (SNRIs) with migraine headache medications known as triptans. When treating moderate to extreme ache, the type of the pain, acute or chronic, needs to be thought-about. Woro_ J, Siwek M. Unwanted results of psychotropic drug interactions with medicinal products and diet supplements containing plant extracts.</p><p> The alternatively prescribed NSAIDs equivalent to ketoprofen and piroxicam have restricted benefit in chronic pain disorders and with lengthy-time period use are associated with important hostile results. 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