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Psychiatric disorders, including depression, psychosis, and bipolar disorder, are common and gaining more acceptance in the United States. Proceedings of the National Academy of Sciences of the United States of America. University Press of America. Mental health policy in trendy America. By utilizing this site, you agree to the Terms of Use and Privacy Policy. Nonbenzodiazepine pharmacodynamics are similar in mechanism of motion to benzodiazepine medicine, performing as GABAA receptor positive allosteric modulators of the benzodiazepine site, and therefore exhibit similar benefits, side effects, and risks. The nonbenzodiazepines are constructive allosteric modulators of the GABAA receptor. GABA is a serious inhibitory neurotransmitter within the central nervous system. 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